Inositol phosphates: synthesis and degradation.

Stereoselective synthesis of inositol phosphates

Pseudomonas putia'a oxidation of benzene affords cis-3,5-cyclohexadiene1,2diol (JJ which serves as a novel precursor for the syntheses of several natural products including (+)-pinitol, (+)-condunto1 F, D-(-)-myo-inositol 1,4,5-trisphosphate and Dmyo-inositol 1-phosphate. The versatility of this approach is further demonstrated by the preparation of other functionalised cyclitol derivatives, in...

Synthesis of inositol glycan cyclic phosphates.

An efficient synthesis of tri-, tetra-, and pentasaccharide cyclic phosphates 1-5, structurally related to natural inositol phosphate glycans, is reported. The title compounds were assembled by PhSeOTf-promoted glycosylation of the known glucosamine precursor, t-butyldimethylsilyl 2-azido-3,6-di-O-benzyl-2-deoxy-beta-D-glucopyranoside (8) with protected 1-methylthio mono-, di-, and trimannoside...

SnapShot: Inositol Phosphates

Inositol phosphates in aquatic systems

While there is a considerable body of research on the abundance and behavior of inositol hexakisphosphate in soils, much less is known regarding its behaviour in aquatic systems. The observed physico-chemical behaviour of this organic P species suggests that in marine and freshwaters, it should be complexed and precipitated by major ions such as calcium, magnesium, iron or aluminium, and thus i...

The metabolism and function of inositol phosphates.

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